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Quality Assessment Results

Srotova_2017.pdf

Status: Completed
Document Type: Diagnostic Study
Assessment Tool: QUADAS-2 (Quality Assessment of Diagnostic Accuracy Studies) - Complete
Assessment completed!
13/13
Next check in: 5 seconds
30.8%
Overall Quality Score
4/13 criteria met

Assessment Details

Assessment Criterion AI Analysis AI Judgment Issues
Was a consecutive or random sample of patients enrolled?
ds_d1_rb1
The document does not explicitly state whether a consecutive or random sample of patients was enrolled. The selection process described involves retrospective review of records and application of inclusion/exclusion criteria, but the sampling method (consecutive or random) is not specified.
no star awarded
Was a case-control design avoided?
ds_d1_rb2
The study explicitly describes a cohort design with clear inclusion/exclusion criteria and follow-up procedures, meeting NOS standards for avoiding case-control design.
star awarded
Did the study avoid inappropriate exclusions?
ds_d1_rb3
The study clearly describes appropriate exclusion criteria that are relevant to the research question about A-waves and neuropathy risk. The exclusions are explicitly stated and justified based on known risk factors for peripheral neuropathy and acute conditions that could confound the results.
star awarded
Are there concerns that the included patients and setting do not match the review question?
ds_d1_ac1
The document does not explicitly state whether the included patients and setting match the review question. While the study describes the patient population and setting, there is no direct comparison or discussion of how these align with the review question regarding A-waves and neuropathy risk. The study focuses on the predictive power of A-waves but does not explicitly address the match between patient characteristics, setting, and the review question.
no star awarded
Were the index test results interpreted without knowledge of the results of the reference standard?
ds_d2_rb1
The document does not explicitly state whether the index test results (A-waves) were interpreted without knowledge of the reference standard results (follow-up NCS/EMG abnormalities). The methods section describes the electrophysiological examination process but does not mention blinding procedures for interpretation of initial A-wave findings.
no star awarded
If a threshold was used, was it pre-specified?
ds_d2_rb2
The document does not explicitly state whether thresholds for A-wave detection were pre-specified prior to data analysis. While the methods describe the electrophysiological examination procedures in detail, there is no mention of pre-defining thresholds for A-wave classification or analysis.
no star awarded
Are there concerns that the index test, its conduct, or interpretation differ from the review question?
ds_d2_ac1
Raw response parsing failed. Original content: ```json { "judgment": "no star awarded", "scoring_rationale": "The document does not explicitly describe whether the index test (A-waves detection in motor nerve conduction studies) was performed ...
no
Is the reference standard likely to correctly classify the target condition?
ds_d3_rb1
Raw response parsing failed. Original content: ```json { "judgment": "star awarded", "scoring_rationale": "The study explicitly describes using nerve conduction studies (NCS) and needle electromyography (EMG) as the reference standard, which a...
no
Were the reference standard results interpreted without knowledge of the results of the index test?
ds_d3_rb2
The document does not explicitly state whether the reference standard results (follow-up NCS/EMG examinations) were interpreted without knowledge of the initial A-wave results (index test). The methods section describes the electrophysiological examination procedures but does not mention blinding procedures for outcome assessment.
no star awarded
Are there concerns that the target condition as defined by the reference standard does not match the question?
ds_d3_ac1
The document does not explicitly define the reference standard for the target condition (neuropathy or radiculopathy) in a way that clearly matches the study question about A-waves predicting future neuropathy. While the study mentions using nerve conduction studies (NCS) and electromyography (EMG) as diagnostic tools, it does not provide detailed criteria for what constitutes neuropathy or radiculopathy in these tests. The absence of explicit diagnostic criteria for the reference standard means we cannot confirm it matches the study question.
no star awarded
Was there an appropriate interval between index test and reference standard?
ds_d4_rb1
The study explicitly states the interval between index test and reference standard, which meets the NOS criterion for an appropriate interval. The interval is documented as being between 12-60 months with a mean of 26.6 ± 14.2 months, which is considered appropriate for the target condition (neuropathy development) given the chronic nature of such conditions.
star awarded
Did all patients receive the same reference standard?
ds_d4_rb2
Raw response parsing failed. Original content: ```json { "judgment": "star awarded", "scoring_rationale": "The study explicitly states that all participants underwent the same electrophysiological examination protocol using standardized method...
star awarded
Were all patients included in the analysis?
ds_d4_rb3
The document does not explicitly state whether all patients were included in the analysis or if there were any withdrawals. While it mentions exclusion criteria and the selection process, there is no discussion of participant retention or explanations for any potential withdrawals during the study period. This lack of explicit information about withdrawals and their potential impact on bias means the criterion is not fully met.
no star awarded
Assessment Summary
13
Total Criteria
4
Criteria Met
9
Issues Found
30.8%
Quality Score

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